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SMB01070

Sigma-Aldrich

Cirsimarin

≥90% (LC/MS-ELSD)

Synonym(s):

5,4′-Dihydroxy-6,7-dimethoxyflavone 4′-O-β-D-glucoside, Cirsimaretin, Cirsimaritin 4′-glucoside, Cirsitakaoside

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About This Item

Empirical Formula (Hill Notation):
C23H24O11
CAS Number:
Molecular Weight:
476.43
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

476.43

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C23H24O11/c1-30-15-8-14-17(19(27)22(15)31-2)12(25)7-13(33-14)10-3-5-11(6-4-10)32-23-21(29)20(28)18(26)16(9-24)34-23/h3-8,16,18,20-21,23-24,26-29H,9H2,1-2H3/t16-,18-,20+,21-,23-/m1/s1

InChI key

RETJLKUBHXTIGH-FZFRBNDOSA-N

General description

Cirsimarin is an antilipogenic flavonoid compound commonly found in plants such as Cirsium japonicum, Scoparia dulcis, Cirsium rhinoceros, and Microtea debilis. Recent research suggests that this naturally occurring metabolite may possess a wide range of biological activities, including cytoprotective, anti-inflammatory, antioxidant, antiviral, antiadipogenic, and antimicrobial properties.

Application

Cirsimarin is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Cirsimarin exerts potent antilipogenic effect and decreases adipose tissue deposition in mice. Cirsimarin could therefore be a potential candidate for the treatment of obesity.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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B Zarrouki et al.
International journal of obesity (2005), 34(11), 1566-1575 (2010-05-12)
We previously reported that the flavonoid cirsimarin exerts in vitro a strong lipolytic activity on isolated adipocytes. This study was therefore designed to evaluate in vivo the effects of cirsimarin on white adipose tissue (WAT) accretion in mice. Male CD1

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