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Key Documents

C1022

Sigma-Aldrich

Carmine

≥42.0% purity, powder

Synonym(s):

Alum lake of carminic acid, Cochineal, Nacarat, Natural Red 4

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About This Item

CAS Number:
Colour Index Number:
75470
EC Number:
UNSPSC Code:
12171500
NACRES:
NA.47

product name

Carmine, powder, ≥42.0% (UV-vis)

Assay

≥42.0% (UV-vis)

form

powder

color

red

solubility

ammonium hydroxide: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

InChI

1S/C22H20O13/c1-4-8-5(2-6(24)9(4)22(33)34)13(25)10-11(15(8)27)16(28)12(18(30)17(10)29)21-20(32)19(31)14(26)7(3-23)35-21/h2,7,14,19-21,23-24,26,28-32H,3H2,1H3,(H,33,34)

InChI key

DGQLVPJVXFOQEV-UHFFFAOYSA-N

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General description

Carmine is a red compound and is generally used with aluminum, iron and other metal salts to enhance its activity. During smear preparation, it is required for chromatin staining in fresh material. In presence of aluminum chloride, it is used for the staining of glycogen.

Application

Carmine has been used for the staining of mammary glands. It has been used for the staining of the chromosomes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A M Touré et al.
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In Hirschsprung disease (HSCR), the absence of myenteric neural ganglia in the distal bowel prevents motility and thereby causes functional intestinal obstruction. Although surgical resection of the aganglionic segment allows HSCR children to survive this condition, a number of patients
Improper chromosome synapsis is associated with elongated RAD51 structures in the maize desynaptic2 mutant.
Franklin AE, et al.
Chromosoma, 112, 17-17 (2003)
Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium.
Tarulli GA, et al.
Breast Cancer Research, 15, R10-R10 (2013)
Dinesh K Ahirwar et al.
Oncogene, 37(32), 4428-4442 (2018-05-04)
The chemokine CXCL12 has been shown to regulate breast tumor growth, however, its mechanism in initiating distant metastasis is not well understood. Here, we generated a novel conditional allele of Cxcl12 in mice and used a fibroblast-specific Cre transgene along
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Williams TM, et al.
Molecular Biology of the Cell, 14, 1027-1027 (2003)

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