60356

Potassium phosphate dibasic

puriss. p.a., ACS reagent, anhydrous, ≥99.0% (T)

• Synonym(s): Dipotassium hydrogenphosphate, Dipotassium phosphate, sec.-Potassium phosphate
• Linear Formula: K₂HPO₄
• CAS Number: 7758-11-4
• Molecular Weight: 174.18
• EC Number: 231-834-5
• MDL number: MFCD00011383
• UNSPSC Code: 12352302
• eCl@ss: 38070212
• PubChem Substance ID: 329758898
• NACRES: NB.24

Properties

• grade: ACS reagent; puriss. p.a.
• Assay: ≥99.0% (T)
• form: powder or crystals
• impurities: ≤0.001% total nitrogen (N)
• loss: ≤1.0% loss on drying, 105 °C
• pH: 8.5-9.6 (25 °C, 50 mg/mL in H₂O)
• anion traces: chloride (Cl^-): ≤30 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg; heavy metals: ≤5 ppm (by ICP-OES)
• SMILES string: [K+].[K+].OP([O-])([O-])=O
• InChI: 1S/2K.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
• InChI key: ZPWVASYFFYYZEW-UHFFFAOYSA-L

Description

General description

Potassium phosphate dibasic is a useful biological buffer having a pH in the range of 8.5-9.6. Potassium phosphate is present in various forms: monobasic (KH₂PO₄), dibasic (KH₂PO₄), and tribasic (K₃PO₄). Potassium phosphate buffers are widely employed in equilibrium dialysis, high performance liquid chromatography (HPLC) and affinity capillary electrophoresis studies.

Application

• beta-lactoglobulin stabilized nanemulsions--Formulation and process factors affecting droplet size and nanoemulsion stability.: This study investigates the impact of formulation and process parameters on the stability and size of beta-lactoglobulin stabilized nanemulsions, potentially involving potassium phosphate dibasic in the formulation process (Ali et al., 2016).


• Correlation of characteristics of gel extrusion module (GEM) tablet formulation and drug dissolution rate.: Examines how the characteristics of gel extrusion in tablet formulations influence drug dissolution rates, relevant for chemists looking into dissolution behavior and possibly involving potassium phosphate dibasic (Juang and Storey, 2003).


• High-performance liquid chromatographic determination of phenylureas by photochemically-induced fluorescence detection.: Discusses a method for detecting phenylureas using high-performance liquid chromatography, which could involve potassium phosphate dibasic as a component of the mobile phase or sample preparation (Munoz de la Pena et al., 2002).


• Assay and purity analysis of diatrizoate sodium in drug product by LC.: This research details a method for assaying and analyzing the purity of diatrizoate sodium, where potassium phosphate dibasic could be part of the chromatographic system (Chellquist et al., 1997).

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable