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32593

Supelco

Cambendazole

VETRANAL®, analytical standard

Synonym(s):

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
Molecular Weight:
302.35
Beilstein:
563292
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry: screening method development and validation.
Jedziniak P, et al.
Journal of Chromatography A, 1216(46), 8165-8172 (2009)
H J Bürger et al.
The Veterinary record, 120(13), 293-296 (1987-03-28)
In order to confirm benzimidazole resistance as recommended at a workshop of the Commission of the European Communities the isolate 'E' of cyathostome strongyles originating from a stud where benzimidazole resistance had been demonstrated by egg hatch tests and by
C Bauer et al.
Veterinary parasitology, 21(3), 189-203 (1986-08-01)
The prevalence of benzimidazole-resistant small strongyles was determined in a survey, conducted on 14 thoroughbred studs, which compared the faecal egg counts of groups of horses before and after treatment with the recommended doses of cambendazole (20 mg kg-1 b.w.)
Nader S Abutaleb et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
Clostridioides difficile, the leading cause of nosocomial infections, is an urgent health threat worldwide. The increased incidence and severity of disease, the high recurrence rates, and the dearth of effective anticlostridial drugs have created an urgent need for new therapeutic
Morphological changes in Capillaria obsignata (Nematoda: Trichuridae) eggs after treatment with cambendazole.
P Dorny et al.
Parasitology research, 74(2), 196-197 (1987-01-01)

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