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The molybdenum cofactor.

The Journal of biological chemistry (2013-03-30)
Ralf R Mendel
ABSTRACT

The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase. The biosynthesis of Moco involves the complex interaction of six proteins and is a process of four steps, which also require iron, ATP, and copper. After its synthesis, Moco is distributed, involving Moco-binding proteins. A deficiency in the biosynthesis of Moco has lethal consequences for the respective organisms.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Molybdenum, powder, 1-5 μm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, powder, <150 μm, 99.99% trace metals basis
Sigma-Aldrich
Molybdenum, nanopowder, <100 nm particle size (TEM), 99.8% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, powder, 10 μm, ≥99.95% trace metals basis
Sigma-Aldrich
Molybdenum, powder, <150 μm, 99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis
Molybdenum, foil, light tested, 50x50mm, thickness 0.009mm, 99.9%
Molybdenum, rod, 200mm, diameter 25mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 15.0mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 6.0mm, centerless ground, 99.9%
Molybdenum, rod, 500mm, diameter 1.5mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 8.0mm, centerless ground, 99.9%
Molybdenum, rod, 500mm, diameter 12mm, centerless ground, 99.9%
Molybdenum, rod, 200mm, diameter 1.25mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 25mm, centerless ground, 99.9%
Molybdenum, rod, 500mm, diameter 15.0mm, centerless ground, 99.9%
Molybdenum, rod, 200mm, diameter 5.0mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 3.0mm, centerless ground, 99.9%
Molybdenum, foil, 25x25mm, thickness 0.5mm, annealed, 99.9%
Molybdenum, wire reel, 100m, diameter 1.25mm, annealed, 99.95%
Molybdenum, foil, 25x25mm, thickness 1.0mm, annealed, 99.9%
Molybdenum, foil, 50x50mm, thickness 1.5mm, annealed, 99.9%
Molybdenum, wire reel, 500m, diameter 0.025mm, hard, 99.95%
Molybdenum, wire reel, 5m, diameter 0.015mm, gold plated, 99.95%
Molybdenum, wire reel, 25m, diameter 1.25mm, annealed, 99.95%
Molybdenum, wire reel, 50m, diameter 0.2mm, as drawn, 99.95%
Molybdenum, foil, 50x50mm, thickness 0.1mm, annealed, 99.9%
Molybdenum, wire reel, 200m, diameter 0.5mm, annealed, 99.95%