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T7511

Supelco

Tripelennamine hydrochloride

analytical standard

Synonym(s):

2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, N-Benzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride, Pyribenzamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H21N3 · HCl
CAS Number:
154-69-8
Molecular Weight:
291.82
EC Number:
205-833-5
MDL number:
MFCD00012815
UNSPSC Code:
41116107
PubChem Substance ID:
329826868
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.Cl

InChI

1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

InChI key

FSSICIQKZGUEAE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

Tripelennamine hydrochloride is an antihistamine drug, which is used in the treatment of bronchitis, asthma and bronchoconstriction.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tripelennamine hydrochloride may be used as a reference standard in the determination of tripelennamine hydrochloride in samples of animal feed by gas chromatography (GC) method, wastewater and urine using high performance liquid chromatography (HPLC) method employing fluorescence detector.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV4290
MKCK8141
MKCH2831
MKBV5910V
MKBR1250V

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Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson TH, et al.
Talanta, 30(4), 251-260 (1983)
C E Johanson et al.
Psychopharmacology, 126(2), 140-146 (1996-07-01)
Twenty volunteers were trained to discriminate between 75 mg tripelennamine (TP) and placebo. During the first four sessions, the drugs were identified prior to ingestion by letter code. During the next six sessions, the procedure was the same except the
J L Lima et al.
Journal of pharmaceutical and biomedical analysis, 14(8-10), 931-938 (1996-06-01)
The construction and evaluation of tripelennamine conventionally-shaped ion-selective electrodes and tubular detectors for the determination of this compound in pharmaceutical formulations are described. Electrodes with conventional configuration have been constructed without an internal reference solution, using several types of immobilized
G Viola et al.
Die Pharmazie, 59(12), 948-951 (2005-01-11)
The influence of mast cell activation on the secretion of prolactin has been studied in rats receiving lysophosphatidylserine, a natural occurring phospholipid with secretagogue activity in these cells. After the i.v. injection of lysophosphatidylserine (10 mg/kg) a plasma prolactin peak
C E Johanson et al.
Experimental and clinical psychopharmacology, 6(4), 427-432 (1998-12-23)
Participants discriminated between tripelennamine and placebo in experiments differing in instructional set. In 1 experiment (SED), participants were told that 1 of the 2 drugs was more sedative-like, and during the other (STIM), 1 was more stimulant-like. During generalization tests
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