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Carnidazole

VETRANAL®, analytical standard

Synonym(s):

[2-(2-Methyl-5-nitro-imidazol-1-yl)ethyl]thiocarbamic acid O-methyl ester

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About This Item

Empirical Formula (Hill Notation):
C8H12N4O3S
CAS Number:
Molecular Weight:
244.27
Beilstein:
620260
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

COC(=S)NCCn1c(C)ncc1[N+]([O-])=O

InChI

1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)

InChI key

OVEVHVURWWTPFC-UHFFFAOYSA-N

General description

Carnidazoles belong to the class of nitroimidazole compounds that are generally utilized for the treatment of various diseases in poultry, cattle and pigs.

Application

Carnidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Eggs by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
  • Environmental water samples by dispersive liquid-liquid microextraction (DLLME), followed by micellar electrokinetic chromatography (MEKC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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[Study of carnidazole (R 25831). A new therapeutic agent for vaginal trichomoniasis].
V Fonzé et al.
Revue medicale de Liege, 34(19), 811-815 (1979-10-01)
P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction.
Hernandez-Mesa, et al.
Journal of Chromatography A, 1341(46), 65-72 (2014)
L Van Vaeck et al.
Biomedical & environmental mass spectrometry, 16(1-12), 121-129 (1988-10-01)
Laser microprobe mass analysis (LAMMA) was used for the structural characterization of polyfunctional drugs and their oxygenated metabolites, in particular the N-oxides. The spectra usually yield the molecular weight as well as intense fragments. The structural information is characteristically distributed
Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry.
Cronly M, et al.
Journal of Chromatography A, 1216(46), 8101-8109 (2009)

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