395137

2-(Trichloroacetyl)pyrrole

99%

• Synonym(s): 2-Pyrrolyl trichloromethyl ketone
• Empirical Formula (Hill Notation): C₆H₄Cl₃NO
• CAS Number: 35302-72-8
• Molecular Weight: 212.46
• MDL number: MFCD00128757
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864647
• NACRES: NA.22

Properties

• Assay: 99%
• mp: 72-74 °C (lit.)
• SMILES string: ClC(Cl)(Cl)C(=O)c1ccc[nH]1
• InChI: 1S/C6H4Cl3NO/c7-6(8,9)5(11)4-2-1-3-10-4/h1-3,10H
• InChI key: BBFDGMDENAEMKF-UHFFFAOYSA-N

Description

General description

2-(Trichloroacetyl)pyrrole is a 2-substituted pyrrole. It undergoes acylation to afford 4-acyl derivatives (4-formyl to 4-hexanoyl).

Application

2-(Trichloroacetyl)pyrrole may be used in the synthesis of following:

• pyrrole-2-carboxylates, tris[2-(2-pyrryl-carboxy)ethyl]amine and tetrakis(2-pyrryl-carboxy-methyl)methane
• 1-oxo-2,3-disubstituted -pyrrolo[1,2-a]pyrazines
• 4-pyridylmethyl 1H-pyrrole-2-carboxyl­ate

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves