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  • Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide.

Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide.

Journal of lipid research (1966-01-01)
Z Selinger, Y Lapidot
ABSTRACT

A simple method is described for the preparation of caprylic, palmitic, stearic, and oleic anhydrides. Reaction of the free fatty acid and dicyclohexylcarbodiimide in carbon tetrachloride at room temperature gives the corresponding anhydrides in high yield (87-94%).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Palmitic acid, ≥98% palmitic acid basis (GC)
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