Skip to Content
Merck
  • Asymmetric synthesis of deoxypolypropionate units via stereoselective hydrogenation of optically active cycloheptatriene.

Asymmetric synthesis of deoxypolypropionate units via stereoselective hydrogenation of optically active cycloheptatriene.

Organic letters (2004-11-19)
Takashi Sugimura, Yasuhiro Sato, Chun Young Im, Tadashi Okuyama
ABSTRACT

Optically active polypropionate units were synthesized in 9-11 steps from 3,5-dimethylphenol. The sequence consists of the Buchner reaction controlled by a chiral 2,4-pentanediol tether and diastereoselective hydrogenation over Raney nickel. [reaction: see text]

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
3,5-Dimethylphenol, ≥99%
SKU
Pack Size
Availability
Price
Quantity