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  • Potentiality of an organometallic labelled streptavidin--biotin system in metalloimmunoassay.

Potentiality of an organometallic labelled streptavidin--biotin system in metalloimmunoassay.

Journal of pharmaceutical and biomedical analysis (1991-01-01)
I Rémy, P Brossier, I Lavastre, J Besançon, C Moïse
ABSTRACT

Biotin labelled with a cymantrene moiety (cyclopentadienyl manganese tricarbonyl complex) is described for the first time. Because this metallo-biotin retains full recognition for the specific glycoprotein avidin (or streptavidin), the labelled streptavidin-biotin system is proposed for use in a solid-phase competition-type metalloimmunoassay in which bovine serum albumin (BSA) is used as a model of applications. Atomic absorption spectrometry is utilized for the detection of the cymantrene-labelled biotin.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cyclopentadienylmanganese(I) tricarbonyl
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