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  • One-pot and efficient synthesis of triazolo[1,2-a]indazole-triones via reaction of arylaldehydes with urazole and dimedone catalyzed by silica nanoparticles prepared from rice husk.

One-pot and efficient synthesis of triazolo[1,2-a]indazole-triones via reaction of arylaldehydes with urazole and dimedone catalyzed by silica nanoparticles prepared from rice husk.

Molecules (Basel, Switzerland) (2011-10-28)
Hooshang Hamidian, Samieh Fozooni, Asadollah Hassankhani, Sayed Zia Mohammadi
ABSTRACT

A novel synthesis of triazolo[1,2-a]indazole-1,3,8-trione derivatives by reaction of urazole, dimedone and aromatic aldehydes under conventional heating and microwave irradiation and solvent-free conditions using silica nanoparticles prepared from rice husk ash as catalyst is described. The new method features high yields, multicomponent reactions and environmental friendliness.

MATERIALS
Product Number
Brand
Product Description

Supelco
5,5-Dimethyl-1,3-cyclohexanedione, for HPLC derivatization, for the determination of aldehyde formaldehyde, ≥99.0%
Sigma-Aldrich
5,5-Dimethyl-1,3-cyclohexanedione, 95%