Skip to Content
Merck

Regulatory properties of AMP deaminases from rat tissues.

The International journal of biochemistry (1991-01-01)
J Spychala, J Marszalek
ABSTRACT

1. Phosphocellulose column chromatography under double gradient conditions (phosphate and KCl) revealed two forms of AMP deaminase in rat heart and brain and a single form in the liver and skeletal muscle. 2. Kinetically all purified AMP deaminases were classified into two categories: those, which elute from the column at lower KCl and Pi concentrations, display low S0.5 value are only moderately affected by MgATP, MgGTP and Pi; and those which elute at higher KCl and Pi concentrations, display high S0.5 values and are strongly regulated by allosteric effectors. 3. Physiological significance of the occurrence of two kinetic forms of AMP deaminase in some tissues is discussed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Guanosine 5′-triphosphate sodium salt hydrate, ≥95% (HPLC), powder
SKU
Pack Size
Availability
Price
Quantity
Sigma-Aldrich
Guanosine 5′-triphosphate sodium salt hydrate, ≥90% (HPLC)
SKU
Pack Size
Availability
Price
Quantity
Sigma-Aldrich
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription
SKU
Pack Size
Availability
Price
Quantity