Skip to Content
Merck
All Photos(3)

Key Documents

S5922

Sigma-Aldrich

Salicylic acid

BioXtra, ≥99.0%

Synonym(s):

2-Hydroxybenzoic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

4.8 (vs air)

Quality Level

vapor pressure

1 mmHg ( 114 °C)

product line

BioXtra

Assay

≥99.0%

form

powder or crystals

technique(s)

tissue culture: suitable (plant)

impurities

≤0.015% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.01%

bp

211 °C (lit.)

mp

158-161 °C (lit.)

solubility

ethanol: 1 M at 20 °C, clear, colorless

density

1.44 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.003%

cation traces

Al: ≤0.001%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.01%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

Application

  • Salinity stress management in agriculture: A study demonstrated the application of salicylic acid in ameliorating salinity stress in barley, revealing its potential to enhance crop resilience to saline environments, thereby contributing to sustainable agricultural practices (Hanif et al., 2024).
  • Enhanced pharmaceutical gel performance: Research on nitrocellulose for prolonged permeation of Levofloxacin HCl-Salicylic Acid In Situ gel emphasized its utility in enhancing drug delivery systems, particularly in treating bacterial infections with improved efficacy (Khaing et al., 2024).
  • Biotechnological production of withanolides: Salicylic acid was applied as an elicitor in the hairy root culture of Withania somnifera, significantly boosting the production of withanolides and phenolic acids, vital for pharmaceutical applications due to their therapeutic properties (Halder and Ghosh, 2024).

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dmitrij Rekhter et al.
Science (New York, N.Y.), 365(6452), 498-502 (2019-08-03)
The phytohormone salicylic acid (SA) controls biotic and abiotic plant stress responses. Plastid-produced chorismate is a branch-point metabolite for SA biosynthesis. Most pathogen-induced SA derives from isochorismate, which is generated from chorismate by the catalytic activity of ISOCHORISMATE SYNTHASE1. Here
S G Owen et al.
British journal of clinical pharmacology, 38(4), 349-355 (1994-10-01)
1. Five rheumatoid patients with a knee joint effusion participated in the study. An aqueous solution (0.1 to 0.2 ml) containing paracetamol, salicylate, diclofenac and [125I]-albumin was injected into a given joint to yield target concentrations of approximately 20 micrograms
Limor Poraty-Gavra et al.
Plant physiology, 161(3), 1172-1188 (2013-01-16)
How plants coordinate developmental processes and environmental stress responses is a pressing question. Here, we show that Arabidopsis (Arabidopsis thaliana) Rho of Plants6 (AtROP6) integrates developmental and pathogen response signaling. AtROP6 expression is induced by auxin and detected in the
E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service