All Photos(1)
About This Item
Linear Formula:
BrC6H4OCF3
CAS Number:
Molecular Weight:
241.01
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
99%
form
liquid
refractive index
n20/D 1.462 (lit.)
density
1.62 g/mL at 25 °C (lit.)
SMILES string
FC(F)(F)Oc1cccc(Br)c1
InChI
1S/C7H4BrF3O/c8-5-2-1-3-6(4-5)12-7(9,10)11/h1-4H
InChI key
WVUDHWBCPSXAFN-UHFFFAOYSA-N
General description
1-Bromo-3-(trifluoromethoxy)benzene undergoes Diels-Alder reaction with lithium diisopropylamide (LDA) in THF and furan, to yield the corresponding 1,4-dihydro-1,4-epoxy-5- or 6-(trifluoromethoxy)naphthalenes.
Application
1-Bromo-3-(trifluoromethoxy)benzene may be used in the preparation of 1,2-dehydro-3-(trifluoromethoxy)benzene. It may be used in the synthesis of new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep [2,2′-bis(diphenylphosphino)-6,6′-ditrifluoromethoxy-1,1′-biphenyl].
accessory
Product No.
Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
145.4 °F - closed cup
Flash Point(C)
63 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
The use of arynes in organic synthesis.
Pellissier H and Santelli M.
Tetrahedron, 59(6), 701-730 (2003)
1, 2-Didehydro-3-and-4-(trifluoromethoxy) benzene: The ?Aryne? Route to 1-and 2-(Trifluoromethoxy) naphthalenes.
Schlosser M and Castagnetti E.
European Journal of Organic Chemistry, 21, 3991-3997 (2001)
A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation.
Zhang D-Y, et al.
Tetrahedron Letters, 53(20), 2556-2559 (2012)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service