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Merck

STIM1 for stimulation of phagocyte NADPH oxidase.

Blood (2014-04-05)
Richard D Ye
PMID24700712
ABSTRACT

In this issue of Blood, Zhang et al show that mice lacking the stromal-interacting molecule 1 (STIM1) gene in bone marrow cells are more susceptible to bacterial infection but are resistant to ischemia/reperfusion injury because of defective activation of phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.

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