Skip to Content
Merck
All Photos(1)

Documents

Y0000769

Promethazine impurity D

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(2RS)-N,N-Dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine S-oxide, Promethazine 5-sulfoxide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H20N2OS
CAS Number:
7640-51-9
Molecular Weight:
300.42
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

promethazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H20N2OS/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)21(20)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

InChI key

OWTCLFIFAFHQIX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Promethazine impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Y0000797

Promethazine for peak identification, European Pharmacopoeia (EP) Reference Standard

P3400000

Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1467

Promethazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1570009

Promethazine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1570029

Promethazine Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP412

Promethazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP778

Isopromethazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP505

Promethazine sulfoxide, British Pharmacopoeia (BP) Reference Standard

PHR2777

Promethazine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ronald J Peters et al.
Journal of drug education, 33(4), 415-425 (2004-07-09)
In the current study, we used a qualitative approach to investigate relevant beliefs and norms associated with codeine and promethazine hydrochloride cough syrup (CPHCS) consumption, initiation, and perceived addiction among 48 alternative school students who identified themselves as current CPHCS
S R Vanapalli et al.
Journal of chromatographic science, 39(2), 70-72 (2001-03-14)
A new assay method has been developed for the quantitation of promethazine (PMZ) with a sensitivity and reproducibility as good as any previously reported method. This method is also capable of quantitatively determining three metabolites of PMZ (monodemethylated, sulphoxidated, and
L Galzigna et al.
Free radical research, 27(5), 501-504 (1998-03-28)
Lactoperoxidase, when incubated with increasing amounts of promethazine (P) and promethazine sulfoxide (PO) catalyzes the formation of promethazine sulfoxide accompanied by oxygen consumption. An intermediate radical of PO can be detected by electron spin resonance (ESR). Catalase or superoxide dismutase
L Galzigna et al.
Free radical biology & medicine, 20(6), 807-811 (1996-01-01)
Promethazine sulfoxide was obtained with a quantitative yield in a horse radish peroxidase-catalyzed reaction of promethazine and hydrogen peroxide and was also prepared by direct chemical synthesis. The enzymatic sulfoxidation of promethazine was studied in vitro as a function of
Xufei Li et al.
Se pu = Chinese journal of chromatography, 30(9), 938-942 (2013-01-05)
Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) intensity of tris(2,2'-bipyridyl) ruthenium, a novel and sensitive method was proposed for the simultaneous determination of CPZ

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service