GF309
NT-4 Protein, Human Recombinant Animal Free
The Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors.
Synonym(s):
NT4, Neurotrophin 4, Neurotrophin 4/5, NT4/5
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Recommended Products
Quality Level
Assay
>98% (SDS-PAGE and HPLC)
impurities
<0.1 μg/mg protein endotoxin (<1EU/μg)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Specificity
Cross Reactivty
Mouse, Rat
Mouse, Rat
Quality
Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
Physical form
Recombinant animal free human NT-4 is manufactured using all non-animal reagents
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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