329207

Dianhydro-D-glucitol

98%

• Synonym(s): 1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
• Empirical Formula (Hill Notation): C₆H₁₀O₄
• CAS Number: 652-67-5
• Molecular Weight: 146.14
• Beilstein: 80510
• EC Number: 211-492-3
• MDL number: MFCD00064827
• UNSPSC Code: 12352201
• PubChem Substance ID: 24859776
• NACRES: NA.22

Properties

• Assay: 98%
• form: solid
• optical activity: [α]20/D +45.2°, c = 3 in H₂O
• mp: 60-63 °C (lit.)
• SMILES string: O[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12
• InChI: 1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1
• InChI key: KLDXJTOLSGUMSJ-JGWLITMVSA-N

Description

Application

Dianhydro-D-glucitol is a greener ingredient widely used as a monomer and building block for a variety of polymers and functional materials, for medical and pharmaceutical applications. It is also used as a fuel or fuel additive.
Applications include:

• Preparation of renewable polyesters for coating applications.
• Synthesis of isosorbide esters such as oligo(isosorbide adipate) (OSA), oligo(isosorbide suberate) (OSS), and isosorbide dihexanoate (SDH) as renewable alternatives to phthalate plasticizers.
• Synthesis of biodegradable porous polyurethane scaffolds for tissue repair and regeneration.
• Synthesis of the aspirin prodrug, isosorbide-2,5-diaspirinate (ISDA).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves