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Merck

Environmental genomics: mechanistic insights into toxicity of and resistance to the herbicide 2,4-D.

Trends in biotechnology (2007-06-20)
Miguel Cacho Teixeira, Paula Duque, Isabel Sá-Correia
RÉSUMÉ

Genomic information and tools are beginning to be used to increase our understanding of how organisms of all types interact with their environment. The study of the expression of all genes, at the genome, transcriptome, proteome and metabolome level, in response to exposure to a toxicant, is known as toxicogenomics. Here, we show how this new field of environmental genomics has enhanced the development of fundamental knowledge on the mechanisms behind the toxicity of and resistance to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). Although 2,4-D is one of the most successfully and widely used herbicides, its intensive use has led to the emergence of resistant weeds and might give rise to several toxicological problems when present in concentrations above those recommended. This review summarizes recent mechanistic insights into 2,4-D toxicity and the corresponding adaptive responses based on studies carried out using Saccharomyces cerevisiae and Arabidopsis thaliana as model organisms.

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Description du produit

Sigma-Aldrich
Acide 2,4-Dichlorophenoxyacétique, 97%
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Sigma-Aldrich
Acide 2,4-Dichlorophenoxyacétique, ≥95%, crystalline
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Supelco
2,4-D, PESTANAL®, analytical standard
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Supelco
2,4-D, PESTANAL®, analytical standard
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Supelco
Acide 2,4-Dichlorophenoxyacétique, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Le tarif et la disponibilité ne sont pas disponibles actuellement.