- Large-scale de novo DNA synthesis: technologies and applications.
Large-scale de novo DNA synthesis: technologies and applications.
Nature methods (2014-05-02)
Sriram Kosuri, George M Church
PMID24781323
RÉSUMÉ
For over 60 years, the synthetic production of new DNA sequences has helped researchers understand and engineer biology. Here we summarize methods and caveats for the de novo synthesis of DNA, with particular emphasis on recent technologies that allow for large-scale and low-cost production. In addition, we discuss emerging applications enabled by large-scale de novo DNA constructs, as well as the challenges and opportunities that lie ahead.
MATÉRIAUX
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Description du produit
Sigma-Aldrich
Deoxyribonucleic acid from human placenta, buffered aqueous solution, sexed, female