P57204

Pyridazine

98%

• Synonyme(s) : 1,2-Diazabenzene, 1,2-Diazine, o-Diazine
• Formule empirique (notation de Hill): C₄H₄N₂
• Numéro CAS: 289-80-5
• Poids moléculaire : 80.09
• Numéro Beilstein : 103906
• Numéro CE : 206-025-5
• Numéro MDL: MFCD00006463
• Code UNSPSC : 12352100
• ID de substance PubChem : 24898697
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 98%
• Indice de réfraction: n20/D 1.524 (lit.)
• Point d'ébullition: 208 °C (lit.)
• Pf: −8 °C (lit.)
• Densité: 1.103 g/mL at 25 °C (lit.)
• Chaîne SMILES: c1ccnnc1
• InChI: 1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H
• Clé InChI: PBMFSQRYOILNGV-UHFFFAOYSA-N

Description

Description générale

Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.

Application

Pyridazine can be used:

• As a building block to synthesize N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine derivatives as GSK-3 inhibitors.
• As a starting material in the synthesis of pharmacologically important pyrrolo[1,2-b]pyridazine derivatives.
• To prepare 1-(6-ethoxy-6-oxohexyl)pyridazin-1-ium bromide and 1-(2-bromoacetyl) pyridazinium bromide ionic liquids as corrosion inhibitors of steel under acidic conditions.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 185.0 °F - closed cup
• Point d'éclair (°C): 85 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)