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Key Documents

SMB00907

Sigma-Aldrich

Nicotinamide riboside chloride

≥97% (HPLC), powder

Synonym(s):

Nicotinamide riboside chloride, Nicotinamide ribose chloride

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About This Item

Empirical Formula (Hill Notation):
C11H15N2O5Cl
CAS Number:
Molecular Weight:
290.70
UNSPSC Code:
12352205
NACRES:
NA.28

biological source

milk

Quality Level

Assay

≥97% (HPLC)

form

powder

color

white to off-white

solubility

10 mg/mL, clear, colorless

shipped in

wet ice

storage temp.

2-8°C

General description

Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk and later discovered to be a NAD(+) precursor.

Application


  • Raising NAD(+) Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation: This study demonstrates the potential of Nicotinamide Riboside Chloride to elevate NAD+ levels, thereby stimulating protein activity that can alleviate heart failure symptoms, highlighting its use as a cellular metabolism booster (Walker et al., 2023).

  • Acute Treatment with Nicotinamide Riboside Chloride Reduces Hippocampal Damage and Preserves the Cognitive Function of Mice with Ischemic Injury: This study investigates the neuroprotective effects of Nicotinamide Riboside Chloride, suggesting its potential in treating neurodegenerative diseases (Cheng et al., 2022).

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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