840030P

06:0 PS

1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

• Synonym(s): PS(6:0/6:0)
• Empirical Formula (Hill Notation): C₁₈H₃₃NO₁₀PNa
• CAS Number: 321862-85-5
• Molecular Weight: 477.42
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (840030P-10mg); pkg of 1 × 25 mg (840030P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840030P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]
• InChI: 1S/C18H34NO10P.Na/c1-3-5-7-9-16(20)26-11-14(29-17(21)10-8-6-4-2)12-27-30(24,25)28-13-15(19)18(22)23;/h14-15H,3-13,19H2,1-2H3,(H,22,23)(H,24,25);/q;+1/p-1/t14-,15+;/m1./s1
• InChI key: OPDYVXCKOQKYDZ-LIOBNPLQSA-M

Description

General description

Phosphatidylserine (PS) is an acidic phospholipid. Approximately 15–33 mol% of PS is present in the inner leaflet of the plasma membrane.

Application

06:0 PS may be used to study its effect on α-syn (α-synuclein) oligomerization by DA (dopamine) and as a phospholipid substrate to determine the kinetic parameters for phospholipase C by chromogenic assay. It has also been used in the preparation of phospholipid vesicles.

Biochem/physiol Actions

Phosphatidylserine (PS) participates in several signaling pathways. This membrane phospholipid controls the Akt (protein kinase B) phosphorylation process.

Packaging

5 mL Clear Glass Sealed Ampule (840030P-10mg)

5 mL Clear Glass Sealed Ampule (840030P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids