1370280

Loratadin-verwandte Verbindung A

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Desloratadin, 8-Chlor-6,11-dihydro-11-(4-piperidinyliden)-5H-benzo[5,6]cyclohepta[1,2,b]pyridin, Clarinex^®, NSC 675447
• Empirische Formel (Hill-System): C₁₉H₁₉ClN₂
• CAS-Nummer: 100643-71-8
• Molekulargewicht: 310.82
• MDL-Nummer: MFCD00871949
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750257
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: loratadine
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
• InChI: 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
• InChIKey: JAUOIFJMECXRGI-UHFFFAOYSA-N
• Angaben zum Gen: human ... HRH1(3269)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Loratadine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Loratadine Orally Disintegrating Tablets
• Loratadine Chewable Tablets
• Loratadine Capsules

Biochem./physiol. Wirkung

Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Rechtliche Hinweise

Clarinex is a registered trademark of Schering Corp.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 390.2 °F - Pensky-Martens closed cup
• Flammpunkt (°C): 199 °C - Pensky-Martens closed cup