N7502
DL-Norvalin
≥98% (HPLC), suitable for HPLC
Synonym(e):
(±)-2-Amino-valeriansäure
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Alle Fotos(2)
About This Item
Lineare Formel:
CH3CH2CH2CH(NH2)COOH
CAS-Nummer:
Molekulargewicht:
117.15
Beilstein:
1721163
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.26
Empfohlene Produkte
product name
DL-Norvalin,
Assay
≥98% (HPLC)
Qualitätsniveau
Form
powder
Methode(n)
HPLC: suitable
Farbe
white
mp (Schmelzpunkt)
>300 °C
SMILES String
CCCC(N)C(O)=O
InChI
1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChIKey
SNDPXSYFESPGGJ-UHFFFAOYSA-N
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Allgemeine Beschreibung
Norvaline is a non-proteinogenic α-amino acid and is also called DL-α-aminovaleric acid. It is produced in Gram-negative microorganisms including Escherichia coli and is also a part of the antifungal peptide produced by Bacillus subtilis.
Anwendung
DL-Norvaline has been used as an internal standard:
- to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
- to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
- for free amino acid analysis in samples of oocytes by liquid chromatography
Biochem./physiol. Wirkung
DL-Norvaline is a neurotransmitter.
Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.
Anwendung
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
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Physical chemistry chemical physics : PCCP, 20(1), 276-283 (2017-12-06)
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