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Merck

A7003

Sigma-Aldrich

Alginsäure aus Braunalgen

powder

Synonym(e):

Alginsäure aus Macrocystis pyrifera (Kelp), Mischpolymer aus Mannuron- und Guluronsäure

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About This Item

Lineare Formel:
(C6H8O6)n
CAS-Nummer:
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
NACRES:
NA.47

Form

powder

Qualitätsniveau

Methode(n)

titration: suitable

Farbe

white to light yellow

pH-Bereich

1.5-3.5

mp (Schmelzpunkt)

300 °C

Löslichkeit

H2O: insoluble, but swells
aqueous base: soluble

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

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Allgemeine Beschreibung

Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae. It is reported to inhibit the reverse transcriptase activity of HIV. Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported. Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported. Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported. It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).

Anwendung

Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.

Sonstige Hinweise

Geradkettige, hydrophile, kolloidale, Poly-Uronsäure hauptsächlich bestehend aus Anhydro-β-D-Mannuronsäureresten mit 1→4-Bindung.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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G Klöck et al.
Applied microbiology and biotechnology, 40(5), 638-643 (1994-01-01)
Alginate is used as a matrix for immunoisolation of cells and tissues in vivo. We have demonstrated previously that commercial alginates contain various fractions of mitogenic impurities and that they can be removed by free flow electrophoresis. The use of
K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component

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