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Merck

94334

Supelco

Formononetin

analytical standard

Synonym(e):

7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-on, 7-Hydroxy-3-(4-methoxyphenyl)-chromon, 7-Hydroxy-4′-methoxy-isoflavon, Biochanin B, Daidzein-4′-methylether, Formonetin

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About This Item

Empirische Formel (Hill-System):
C16H12O4
CAS-Nummer:
Molekulargewicht:
268.26
Beilstein:
237979
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥98.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

2-8°C

SMILES String

COc1ccc(cc1)C2=COc3cc(O)ccc3C2=O

InChI

1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3

InChIKey

HKQYGTCOTHHOMP-UHFFFAOYSA-N

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Allgemeine Beschreibung

Formononetin belongs to the isoflavones class of polyphenols.

Anwendung

Formononetin has been used as a reference standard for the determination of formononetin in:
  • Cow, goat, sheep and human milk samples by magnetic-micro-dispersive solid-phase extraction (m-μ-dSPE) combined with ultra-high performance liquid chromatography-triple quadrupole electrospray ionization-tandem mass spectrometry (UHPLC-QqQ-ESI-MS/MS) operating under the multiple reaction monitoring (MRM) mode of detection.
  • Dairy products by quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction procedure and UHPLC-QqQ-ESI-MS/MS with MRM mode of detection.

It may be used as a reference standard for the determination of formononetin in:
  • Natural products by turbulent flow chromatography liquid chromatography-high resolution mass spectrometry (TFC LC-HRMS).
  • Soy-drinks by gas chromatography combined with MS/MS operating on electron ionization (EI) mode.
  • Rat plasma by UHPLC-QqQ-ESI-MS/MS.

Biochem./physiol. Wirkung

Isoflavone found in red clover. Effective against Giardia lamblia infection, at least partially by inducing detachment of trophozoites from intestinal mucosa.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Slide 1 of 10

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Development of liquid chromatography-tandem mass spectrometry method for analysis of polyphenolic compounds in liquid samples of grape juice, green tea and coffee.
Sapozhnikova Y.
Food Chemistry, 150, 87-93 (2014)
Simultaneous determination of formononetin, calycosin and rhamnocitrin from Astragalus complanatus by UHPLC-MS-MS in rat plasma: application to a pharmacokinetic study.
Li Y, et al.
Journal of Chromatographic Science, 54(9), 1605-1612 (2016)
Multiresidue analysis of oestrogenic compounds in cow, goat, sheep and human milk using core-shell polydopamine coated magnetic nanoparticles as extraction sorbent in micro-dispersive solid-phase extraction followed by ultra-high-performance liquid chromatography tandem mass spectrometry
Socas-Rodriguez B, et al.
Analytical and Bioanalytical Chemistry, 410(7), 2031-2042 (2018)
Fast derivatization procedure for the analysis of phytoestrogens in soy milk by gas chromatography tandem mass spectrometry.
Benedetti B, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 137(7), 62-70 (2018)
Multiresidue determination of estrogens in different dairy products by ultra-high-performance liquid chromatography triple quadrupole mass spectrometry.
Socas-Rodriguez B, et al.
Journal of Chromatography A, 1496(7), 58-67 (2017)

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