437786

Diethylchlormalonat

95%

• Lineare Formel: ClCH(CO₂C₂H₅)₂
• CAS-Nummer: 14064-10-9
• Molekulargewicht: 194.61
• EG-Nummer: 237-913-0
• MDL-Nummer: MFCD00009140
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24867397
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: liquid
• Brechungsindex: n20/D 1.432 (lit.)
• Dichte: 1.204 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; ester
• SMILES String: CCOC(=O)C(Cl)C(=O)OCC
• InChI: 1S/C7H11ClO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
• InChIKey: WLWCQKMQYZFTDR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K₂CO₃-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs₂CO₃ in the presence of elemental S₈ or Se_n to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H314,H335,H400
• P-Sätze: P261 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter