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  • Controlled synthesis and alkaline earth ion binding of switchable formamidoxime-based crown ether analogs.

Controlled synthesis and alkaline earth ion binding of switchable formamidoxime-based crown ether analogs.

Chemical communications (Cambridge, England) (2012-07-04)
Yi Yan, Weiwen Zhao, Ganga Viswanathan Bhagavathy, Alexandre Faurie, Nicholas J Mosey, Anne Petitjean
PMID22751352
ABSTRACT

The partial positive charge of amide protons is used to promote macrocyclization and form crown-ether analogs. Their deprotonation generates very selective pH-switchable alkaline earth ion receptors only in the presence of an appropriate substrate.