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SML0530

Sigma-Aldrich

Clonixin

≥98% (HPLC)

Synonym(s):

2-[(3-Chloro-2-methylphenyl)amino]-3-pyridinecarboxylic acid, CBA 93626, Chlonixin, Clonixic acid, Clonixin, Clonixine, NSC 335505, Sch 10304

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About This Item

Empirical Formula (Hill Notation):
C13H11ClN2O2
CAS Number:
17737-65-4
Molecular Weight:
262.69
MDL number:
MFCD00864292
UNSPSC Code:
12352200
PubChem Substance ID:
329825534
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

room temp

SMILES string

Cc1c(Cl)cccc1Nc2ncccc2C(O)=O

InChI

1S/C13H11ClN2O2/c1-8-10(14)5-2-6-11(8)16-12-9(13(17)18)4-3-7-15-12/h2-7H,1H3,(H,15,16)(H,17,18)

InChI key

CLOMYZFHNHFSIQ-UHFFFAOYSA-N

Biochem/physiol Actions

Clonixin is a non steroidal anti inflammatory drug (NSAID) with analgesic properties. The compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David Douglas et al.
Journal of food protection, 75(7), 1270-1277 (2012-09-18)
β-Lactam antibiotics are the most commonly used drugs on dairy farms. β-Lactam residues in milk are kept out of the human milk supply with good agricultural practices and mandatory truck screening performed by the dairy industry under Appendix N of
Sharla M Peters et al.
Veterinary immunology and immunopathology, 148(3-4), 236-242 (2012-06-01)
Non-steroidal anti-inflammatory drugs (NSAID) are a family of chemicals that function to reduce pain, fever, and inflammation, and they are commonly used in people and animals for this purpose. Currently there are no NSAIDs approved for the management of inflammation
Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens.
F Yang et al.
Journal of veterinary pharmacology and therapeutics, 36(1), 85-88 (2012-02-02)
David R Paull et al.
Veterinary anaesthesia and analgesia, 39(5), 539-549 (2012-04-25)
To evaluate the analgesic efficacy of the NSAIDs flunixin and meloxicam administered locally to the scrotum before ring castration. Randomised, controlled, prospective study. Forty eight single born male Merino lambs. Lambs, aged approximately 4 weeks, were allocated to four groups
L W Kissell et al.
Journal of dairy science, 95(12), 7151-7157 (2012-10-09)
The objective of this study was to determine if the plasma pharmacokinetics and milk elimination of flunixin (FLU) and 5-hydroxy flunixin (5OH) differ following intramuscular and subcutaneous injection of FLU compared with intravenous injection. Twelve lactating Holstein cows were used
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