GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
UniProtKB ID:
Gene ID:
- Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
- Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
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Small Molecule - Agonist
Product Number
Description
Species
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Glycine, puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance),
Species
rat
Glycine, meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance),
Species
rat
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GRIN2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-phospho NMDAR2A (Ser1459), ,
Species Reactivity
human
Application
immunocytochemistry
western blot
western blot
Anti-NMDAR2A&B Antibody, pan, Chemicon®, from rabbit,
Species Reactivity
avian, guinea pig, human, mouse, rabbit, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Species Reactivity
mouse, rat
Application
western blot
Anti-NMDAR2A Antibody, serum, Chemicon®,
Species Reactivity
fish, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Blocker
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Inhibitor
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species