Skip to Content
Merck

Tophaceous pseudogout of the thoracic spine.

Acta neurochirurgica (2012-03-01)
Vasisht Srinivasan, Henry Kesler, Mahlon Johnson, Howard Dorfman, Kevin Walter
ABSTRACT

Calcium pyrophosphate dihydrate deposition disease (CPDD, tophaceous pseudogout) is a rare crystal arthropathy characterized by pyrophosphate crystal deposition in joints, synovitis and chondrocalcinosis on imaging. We present the case of a 72-year-old man with 6 months of left chest pain; magnetic resonance imaging revealed a T9/T10 herniated disc. Intraoperatively, the material was sent for pathological analysis revealing pseudogout. Axial calcium pyrophosphate crystal deposition is rare but reported in the literature and found at the craniocervical junction and skull. Spinal calcium pyrophosphate crystal deposition is rare in the thoracic spine. It is often asymptompatic and can involve the disc or ligaments. This case demonstrates a unique presentation of CPDD.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Calcium phosphate, amorphous, nanopowder, <150 nm particle size (BET)