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  • Chain-like assembly of gold nanoparticles on artificial DNA templates via 'click chemistry'.

Chain-like assembly of gold nanoparticles on artificial DNA templates via 'click chemistry'.

Chemical communications (Cambridge, England) (2007-12-20)
Monika Fischler, Alla Sologubenko, Joachim Mayer, Guido Clever, Glenn Burley, Johannes Gierlich, Thomas Carell, Ulrich Simon
PMID18092076
ABSTRACT

We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition ('click chemistry'), resulting in a chain-like assembly of nanoparticles on the DNA template.

MATERIALS
Product Number
Brand
Product Description
928224
Sigma-Aldrich
Gold nanoparticles, 70 nm diameter, azide functionalized, 1ml, OD 50, in water
928275
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Gold nanoparticles, 20 nm diameter, azide functionalized, 1ml, OD 50, in water
928216
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Gold nanoparticles, 80 nm diameter, azide functionalized, 1ml, OD 50, in water
928208
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Gold nanoparticles, 90 nm diameter, azide functionalized, 1 ML, OD 50, in water
928240
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Gold nanoparticles, 50 nm diameter, azide functionalized, 1 ML, OD 50, in water
927864
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Gold nanoparticles, 5 nm diameter, azide functionalized, 1 ML, OD 50, in water
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Gold nanoparticles, 30 nm diameter, azide functionalized, 1ml, OD 50, in water
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Gold nanoparticles, 60 nm diameter, azide functionalized, 1ml, OD 50, in water
928259
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Gold nanoparticles, 40 nm diameter, azide functionalized, 1ml, OD 50, in water
927848
Sigma-Aldrich
Gold nanoparticles, 15 nm diameter, azide functionalized, 1ml, OD 50, in water