SML0037

Ceftibuten hydrate

90-102% anhydrous basis (HPLC)

• Synonym(s): (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
• Empirical Formula (Hill Notation): C₁₅H₁₄N₄O₆S₂ · xH₂O
• CAS Number: 97519-39-6
• Molecular Weight: 410.42 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 329825107
• UNSPSC Code: 51284115
• MDL number: MFCD20488049
• Assay: 90-102% anhydrous basis (HPLC)
• Form: crystalline powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: 90-102% anhydrous basis (HPLC)
• form: crystalline powder
• storage condition: desiccated
• color: white to pale yellow
• solubility: DMSO: ≥50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: O.Nc1nc(cs1)\C(=C\CC(O)=O)C(=O)N[C@H]2[C@H]3SCC=C(N3C2=O)C(O)=O
• InChI: 1S/C15H14N4O6S2.H2O/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19;/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25);1H2/b6-1-;/t10-,13-;/m1./s1
• InChI key: JMLVKZRNRBPPDZ-TXOBIQCCSA-N

Description

General description

Chemical structure: β-lactam

Biochem/physiol Actions

Ceftibuten is a β-lactam antibiotic with antibacterial activity. It is effective for mild-to-moderate respiratory infections. It displays high stability against extended-spectrum β-lactamases producing bacteria.

Ceftibuten is a third generation cephalosporin antibiotic

Third generation cephalosporin antibiotic

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable