H6904

6β-Hydroxycortisol

synthetic (organic), ≥98%, organic anion transporter 3 substrate, powder

• Synonym(s): 4-Pregnene-6,11β,17,21-tetrol-3,20-dione
• Empirical Formula (Hill Notation): C₂₁H₃₀O₆
• CAS Number: 3078-34-0
• Molecular Weight: 378.46
• UNSPSC Code: 51111800
• PubChem Substance ID: 24895777
• NACRES: NA.77
• MDL number: MFCD00200405
• Assay: ≥98%
• Form: powder

Properties

• Product Name: 6β-Hydroxycortisol, ≥98%
• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥98%
• form: powder
• technique(s): HPLC: suitable
• solubility: methanol: 50 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC12CCC(=O)C=C1C(O)CC3C4CC[C@](O)(C(=O)CO)C4(C)CC(O)C23
• InChI: 1S/C21H30O6/c1-19-5-3-11(23)7-14(19)15(24)8-12-13-4-6-21(27,17(26)10-22)20(13,2)9-16(25)18(12)19/h7,12-13,15-16,18,22,24-25,27H,3-6,8-10H2,1-2H3/t12?,13?,15?,16?,18?,19?,20?,21-/m0/s1
• InChI key: GNFTWPCIRXSCQF-JFQOUMBGSA-N

Description

Application

6β-Hydroxycortisol has been used in liquid chromatography with tandem mass spectrometry (LC/MS/MS) analysis to confirm the human embryonic kidney (HEK293) cell-based conversion of parent cortisol to 6β-hydroxycortisol (6βOH) metabolites.

Biochem/physiol Actions

6β-Hydroxycortisol is a metabolite of cortisol.

6β-Hydroxycortisol serves as a substrate for the organic anion transporter 3 (OAT3) and the multidrug and toxin extrusion proteins (MATE1 and MATE-2K).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)