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Merck

B cell conducts the lymphocyte orchestra.

Journal of autoimmunity (2007-03-17)
Pierre Youinou
ABSTRACT

The interest for B cells has recently been revived. They normally play a role in the development, the regulation, as well as the activation of lymphoid architecture: they regulate dendritic cells and T-cell subsets function through cytokine production. Receptor editing is also essential in B cells and aids in preventing autoimmunity. Both abnormalities in the distribution of B-cell subsets and clinical benefit response to B-cell depletion in autoimmune states illustrate their importance. A new area has thus been reached, whereby B lymphocytes return as a significant contributor to autoimmune disorders.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, Lentiviral Particles, B-Cell Activation
Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock, B-Cell Activation
Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, DNA, B-Cell Activation