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  • Efficacy of ofloxacin and other ototopical preparations for chronic suppurative otitis media in children.

Efficacy of ofloxacin and other ototopical preparations for chronic suppurative otitis media in children.

The Pediatric infectious disease journal (2001-02-15)
C D Bluestone
ABSTRACT

The safety and efficacy of ototopical preparations, such as ofloxacin, in the treatment of CSOM in infants and children do not currently have approval by the FDA even though ofloxacin is FDA-approved for treatment of CSOM that occurs in adults. However, treatment with ofloxacin is FDA-approved when AOM occurs in children who have a tympanostomy tube in place, and effective treatment of this acute infection should prevent the subsequent development of CSOM.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ofloxacin, fluoroquinolone antibiotic
USP
Ofloxacin, United States Pharmacopeia (USP) Reference Standard
Ofloxacin, European Pharmacopoeia (EP) Reference Standard
Supelco
Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Ofloxacin, VETRANAL®, analytical standard