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  • Reduction of trial-to-trial variability in functional near-infrared spectroscopy signals by accounting for resting-state functional connectivity.

Reduction of trial-to-trial variability in functional near-infrared spectroscopy signals by accounting for resting-state functional connectivity.

Journal of biomedical optics (2013-01-08)
Xiao-Su Hu, Keum-Shik Hong, Shuzhi Sam Ge
ABSTRACT

The reduction of trial-to-trial variability (TTV) in task-evoked functional near-infrared spectroscopy signals by considering the correlated low-frequency spontaneous fluctuations that account for the resting-state functional connectivity in the brain is investigated. A resting-state session followed by a task-state session of a right hand finger-tapping task has been performed on five subjects. Significant ipsilateral and bilateral resting-state functional connectivity has been detected at the subjects' motor cortex using the seed correlation method. The correlation coefficients obtained during the resting-state are used to reduce the TTV in the signals measured during the task sessions. The results suggest that correlated spontaneous low-frequency fluctuations contribute significantly to the TTV in the task evoked fNIRS signals.

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