Skip to Content
Merck
All Photos(1)

Key Documents

179523

Sigma-Aldrich

Dimethyl suberimidate dihydrochloride

98%

Synonym(s):

DMS, Dimethyl ester octanediimidic acid dihydrochloride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3OC(=NH)CH2(CH2)4CH2C(=NH)OCH3 · 2HCl
CAS Number:
Molecular Weight:
273.20
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

mp

213-214 °C (lit.)

SMILES string

Cl.COC(=N)CCCCCCC(=N)OC

InChI

1S/C10H20N2O2.2ClH/c1-13-9(11)7-5-3-4-6-8-10(12)14-2;;/h11-12H,3-8H2,1-2H3;2*1H

InChI key

ILKCDNKCNSNFMP-UHFFFAOYSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

General description

Dimethyl suberimidate dihydrochloride acts as a cross-linking agent for amino groups. It is used in the treatment of avian myeloblastosis virus (AMV).

Application

Reactant involved in:
  • Chemical modification of tyrosinase for coupling to produce biocatalytic enzymatic flow-through detectors
  • Cross-linker for synthesis of collagen-calcium phosphate composites

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

G Russ et al.
Acta virologica, 20(4), 336-338 (1976-08-01)
Treatment of intact avian myeloblastosis virus (AMV) with dimethyl suberimidate dihydrochloride (DMS), a cross-linking agent specific for amino groups, was found to result in progressive cross-linking among viral proteins, as revealed by polyacrylamide gel electrophoresis (PAGE) in the presence of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service