Recommended Products
Assay
>95% (SDS-PAGE)
Quality Level
form
liquid
contains
≤0.1% sodium azide as preservative
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−20°C
General description
Native IgG1 from human myeloma plasma.
Native IgG1 from human myeloma plasma. Purified from plasma of patients with myelomas producing IgG1 with kappa light chains.
Warning
Toxicity: Standard Handling (A)
Physical form
In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
Preparation Note
Prepared from plasma that was shown by certified tests to be negative for HBsAg and for antibodies to HCV, HBc, HIV-1 and HIV-2.
Other Notes
Single arc by immunoelectrophoresis against antiserum to whole human sera and human κ free and bound light chain. Note: the heavy chain of myeloma IgGs may appear as either a single or double band on gel electrophoresis. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
R B Cejas et al.
Scientific reports, 11(1), 10981-10981 (2021-05-28)
Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed
Liliane Khoryati et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(9), 2221-2231 (2016-03-19)
Plasmacytoid dendritic cells (PDCs) play a central role in pathogenesis of systemic lupus erythematosus (SLE) through their unique ability to produce large amounts of type I interferon (IFN) upon Toll-like receptor 7 (TLR-7) and TLR-9 triggering. PDCs express specific surface
Anna Moroz et al.
Bioconjugate chemistry, 29(10), 3476-3482 (2018-09-20)
The swell of experimental imaging technologies to noninvasively measure immune checkpoint protein expression presents the opportunity for rigorous comparative studies toward identifying a gold standard. 89Zr-atezolizumab is currently in man, and early data show tumor targeting but also abundant uptake
Lili Huang et al.
Journal of leukocyte biology, 80(4), 905-914 (2006-08-05)
LFA-1 (alpha(L)beta(2)) mediates cell-cell and cell-extracellular matrix adhesions essential for immune and inflammatory responses. One critical mechanism regulating LFA-1 activity is the conformational change of the ligand-binding alpha(L) I domain from low-affinity (LA), closed form, to the high-affinity (HA), open
Jorg C de Ruijter et al.
FEMS yeast research, 17(1) (2016-12-14)
Cost-effective manufacturing of biopharmaceuticals in non-mammalian hosts still requires tremendous efforts in strain development. In order to expedite identification of novel leads for strain engineering, we used a transposon-mutagenized yeast genomic DNA library to create a collection of Saccharomyces cerevisiae
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service