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Key Documents

O3303

Sigma-Aldrich

1,8-Octanediol

98%

Synonym(s):

Octamethylene glycol

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About This Item

Linear Formula:
HO(CH2)8OH
CAS Number:
Molecular Weight:
146.23
Beilstein:
1633499
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

bp

172 °C/20 mmHg (lit.)

mp

57-61 °C (lit.)

SMILES string

OCCCCCCCCO

InChI

1S/C8H18O2/c9-7-5-3-1-2-4-6-8-10/h9-10H,1-8H2

InChI key

OEIJHBUUFURJLI-UHFFFAOYSA-N

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Application

1,8-Octanediol can undergo:
  • Polycondensation with citric acid to form biodegradable poly(1,8-octanediol citrate)(POC) crosslinked bioelastomer which can be blended with various additives.
  • Fischer esterification with dicarboxylic acids to form diol-based macromers.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

248.0 °F - closed cup

Flash Point(C)

120 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kai-Hee Huong et al.
International journal of biological macromolecules, 116, 217-223 (2018-05-04)
Long carbon chain alkanediols are used in the production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)], however these substrates possess high toxicity towards bacterial cells. This study demonstrated the effective utilisation of a long carbon chain alkanediol, namely 1,8-octanediol, to enhance the yield and
Chitin nanocrystal enhanced wet adhesion performance of mussel-inspired citrate-based soft-tissue adhesive.
Xu Y, et al.
Carbohydrate Polymers, 190, 324-330 (2018)
Synthesis and Characterization of Diol-Based Unsaturated Polyesters: Poly (diol fumarate) and Poly (diol fumarate-co-succinate).
Tatara AM, et al.
Biomacromolecules, 18(6), 1724-1735 (2017)
Yali Ji et al.
Journal of materials science. Materials in medicine, 27(2), 30-30 (2015-12-26)
Marine mussels tightly adhering to various underwater surfaces inspires human to design adhesives for wet tissue adhesion in surgeries. Characterization of mussel adhesive plaques describes a matrix of proteins containing 3,4-dihydroxyphenylalanine (DOPA), which provides strong adhesion in aquatic conditions. Several
Eun Ji Chung et al.
Journal of tissue engineering and regenerative medicine, 11(3), 704-712 (2014-11-22)
Bone-patellar tendon-bone (BPTB) autografts are the gold standard for anterior cruciate ligament (ACL) reconstruction because the bony ends allow for superior healing and anchoring through bone-to-bone regeneration. However, the disadvantages of BPTB grafts include donor site morbidity and patellar rupture.

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