328650

Potassium tert-butoxide solution

1.0 M in THF

• Synonym(s): Potassium tert-butylate, Potassium-2-methylpropan-2-olate solution
• Linear Formula: (CH₃)₃COK
• CAS Number: 865-47-4
• Molecular Weight: 112.21
• Beilstein: 3556712
• MDL number: MFCD00012162
• UNSPSC Code: 12352103
• PubChem Substance ID: 24859391
• NACRES: NA.23

Properties

• form: liquid
• Quality Level: 200
• reaction suitability: core: potassium
• concentration: 1.0 M in THF
• density: 0.902 g/mL at 25 °C
• SMILES string: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI key: LPNYRYFBWFDTMA-UHFFFAOYSA-N

Description

General description

Potassium tert-butoxide solution is a strong non nucleophilic base. It is capable of deprotonating carbon and other Bronsted acids. Reagent solutions in tert-BuOh may be prepared by reacting anhydrous alcohol with potassium in nitrogen atmosphere.

Application

Potassium tert-butoxide solution(t-BuOK) can be used:

• As a catalyst for the interesterification of rapeseed oil with methyl acetate.
• To promote Sommelet–Hauser rearrangements of N-benzylic amino acid-derived ammonium ylides under mild conditions.
• As a metal-organic precursor in the synthesis of KNbO₃ ferroelectric films by the chemical vapor deposition method.
• To prepare 3-potassiooxamethylpyridine catalyst.
• As a strong alkoxide base reagent.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H314,H335,H336,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH014,EUH019
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 1
• Flash Point(F): -2.2 °F - closed cup
• Flash Point(C): -19 °C - closed cup