34865

Tetrahydrofuran

≥99.9%, suitable for HPLC, inhibitor-free

• Synonym(s): THF, Butylene oxide, Oxolane, Tetramethylene oxide
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• Beilstein: 102391
• EC Number: 203-726-8
• MDL number: MFCD00005356
• UNSPSC Code: 41116105
• PubChem Substance ID: 329755073
• NACRES: NA.21

Properties

• product name: Tetrahydrofuran, inhibitor-free, suitable for HPLC, ≥99.9%
• vapor density: 2.5 (vs air)
• Quality Level: 100
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• Assay: ≥99.9%
• form: liquid
• autoignition temp.: 610 °F
• expl. lim.: 1.8-11.8 %
• technique(s): HPLC: suitable
• impurities: ≤0.0005% non-volatile matter; ≤0.002% free acid (as CH₃COOH); ≤0.05% peroxides (as H₂O₂); ≤0.05% water (Karl Fischer)
• evapn. residue: ≤0.0005%
• color: APHA: ≤10
• refractive index: n20/D 1.407 (lit.)
• pH: ~7
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• density: 0.889 g/mL at 25 °C (lit.)
• absorption: ≤0.0044 at 315 nm; ≤0.005 at 350 nm; ≤0.005 at 400 nm; ≤0.02 at 300 nm; ≤0.046 at 275 nm; ≤0.18 at 250 nm; ≤0.26 at 245 nm; ≤1.0 at 212 nm
• UV absorption: λ: 245 nm A_max: ≤0.26; λ: 275 nm A_max: ≤0.046; λ: 315 μm A_max: ≤0.0044
• suitability: complies for IR spectroscopy
• application(s): food and beverages
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

Tetrahydrofuran (THF) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THF forms a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV).

Application

Suitable for HPLC, spectrophotometry, environmental testing

Tetrahydrofuran may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)- 1,3-diaminopentane (117) polymer, respectively.

Other Notes

Important notice

• The article number 34865-4X2.5L will be discontinued. Please order the single bottle 34865-2.5L which is physically identical with the same exact specifications.
• The article number 34865-6X1L will be discontinued. Please order the single bottle 34865-1L which is physically identical with the same exact specifications.

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Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H319,H335,H336,H351
• Precautionary Statements: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): -6.2 °F - closed cup
• Flash Point(C): -21.2 °C - closed cup