P-120

Pregabalin solution

10.0 mg/mL in water, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₈H₁₇NO₂
• CAS Number: 148553-50-8
• Molecular Weight: 159.23
• MDL number: MFCD00906155
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820077
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: USDEA Schedule V
• concentration: 10.0 mg/mL in water
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: CC(CC([H])(CN)CC(O)=O)C
• InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
• InChI key: AYXYPKUFHZROOJ-UHFFFAOYSA-N

Description

General description

Pregabalin, marketed as the anticonvulsant drug Lyrica, is used in the treatment of epilepsy and generalized anxiety disorder. Along with other anticonvulsants such as gabapentin and levetiracetam, pregabalin is also used to treat neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.

Application

• An artifactual solution degradant of pregabalin due to adduct formation with acetonitrile catalyzed by alkaline impurities during HPLC sample preparation.: This study highlights the challenges in analytical chemistry, particularly the artifact formation in pregabalin solutions under specific conditions, emphasizing the need for rigorous control in pharmaceutical analysis to ensure product stability and efficacy (Lin et al., 2019).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable