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  • Highly cis-selective cyclopropanations with ethyl diazoacetate using a novel Rh(I) catalyst with a chelating N-heterocyclic iminocarbene ligand.

Highly cis-selective cyclopropanations with ethyl diazoacetate using a novel Rh(I) catalyst with a chelating N-heterocyclic iminocarbene ligand.

Organic letters (2008-12-26)
Marianne Lenes Rosenberg, Alexander Krivokapic, Mats Tilset
ABSTRACT

A structurally characterized Rh(I) iminocarbene complex (N,C)Rh(CO)Cl is activated with AgOTf to act as a highly cis-selective catalyst for the cyclopropanation of substituted styrenes and other alkenes with ethyl diazoacetate (11 examples, 10-99% yield, up to >99% cis-selectivity).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ethyl diazoacetate, contains ≥13 wt. % dichloromethane