- Synthesis and molecular mechanical studies of antiviral copper(II) complexes with morpholinebiguanide drug.
Synthesis and molecular mechanical studies of antiviral copper(II) complexes with morpholinebiguanide drug.
Roumanian archives of microbiology and immunology (2002-02-16)
G Patrinoiu, L Patron, J Weinberg, S Nita, A Meghea
PMID11845440
ABSTRACT
The synthesis and characterization of new Cu(II) complexes with morpholinebiguanide drug are described. The complexes formed have been characterized by elemental analysis, IR, UV-VIS, conductance measurements, EPR spectra and magnetic susceptibility measurements. Their biological activity is supported by the experimental data and enhanced by the theoretical ones. The morpholinebiguanide ligand and their copper(II)-complexes were studied by molecular mechanics program.
MATERIALS