- An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3.
An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3.
The Journal of steroid biochemistry and molecular biology (2013-02-12)
R Fraga, B López-Pérez, K Sokolowska, A Guini, T Regueira, S Díaz, A Mouriño, M A Maestro
PMID23396126
ABSTRACT
The synthesis of 1α,25-dihydroxy-20-epi-vitamin D3 (1) by Pd(0)-catalyzed coupling between the boronate ester (2) and the enol triflate (3) is described. This article is part of a Special Issue entitled 'Vitamin D Workshop'.
MATERIALS
Product Number
Brand
Product Description
Calcitriol, European Pharmacopoeia (EP) Reference Standard
Supelco
1α,25-Dihydroxyvitamin D3 solution, 5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®