Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles.

Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles.

Chemical communications (Cambridge, England) (2012-03-14)

Lukas C Gerber, Nadine Moser, Norman A Luechinger, Wendelin J Stark, Robert N Grass

ABSTRACT

Lanthanum oxide nanoparticles were utilized to scavenge phosphate from microbial growth media for the use of targeted nutrient starvation as an antimicrobial strategy. Only in phosphate poor environments a toxic effect was observed. The effect was shown on Escherichia coli, Staphylococcus carnosus, Penicillium roqueforti, and Chlorella vulgaris.

MATERIALS

Product Number

Brand

Product Description

199923

Sigma-Aldrich

Lanthanum(III) oxide, 99.99% trace metals basis

289205

Supelco

Lanthanum(III) oxide, suitable for AAS, ≥99.9%

L4000

Sigma-Aldrich

Lanthanum(III) oxide, ≥99.9%

203556

Sigma-Aldrich

Lanthanum(III) oxide, 99.999% trace metals basis

634271

Sigma-Aldrich

Lanthanum(III) oxide, nanopowder, <100 nm particle size (TEM), 99% trace metals basis