- Oxo-tethered ruthenium(II) complex as a bifunctional catalyst for asymmetric transfer hydrogenation and H2 hydrogenation.
Oxo-tethered ruthenium(II) complex as a bifunctional catalyst for asymmetric transfer hydrogenation and H2 hydrogenation.
Journal of the American Chemical Society (2011-08-30)
Taichiro Touge, Tomohiko Hakamata, Hideki Nara, Tohru Kobayashi, Noboru Sayo, Takao Saito, Yoshihito Kayaki, Takao Ikariya
PMID21870824
ABSTRACT
Newly developed oxo-tethered Ru amido complexes (R,R)-1 and their HCl adducts (R,R)-2 exhibited excellent catalytic performance for both asymmetric transfer hydrogenation and the hydrogenation of ketonic substrates under neutral conditions without any cocatalysts to give chiral secondary alcohols with high levels of enantioselectivity.